Fighters
Donkey Kong: Mario and Donkey Kong debuted in this game.
The Legend of Zelda: Link and Zelda debuted in this game.
Metroid: Samus and Ridley debuted in this game.- Metroid Prime: Dark Samus debuted in this game.
Super Mario World: Yoshi debuted in this game.
Kirby's Dream Land: Kirby and King Dedede debuted in this game.
Star Fox: Fox and Falco debuted in this game.
Pokémon Red and Green: Pikachu, Jigglypuff, Mewtwo and Pokémon Trainer debuted in this game.- Mario Bros. (Game & Watch): Luigi debuted in this game.
EarthBound: Ness debuted in this game.
F-Zero: Captain Falcon debuted in this game.- Super Mario Bros.: Peach, Bowser and Piranha Plant debuted in this game.
- Super Mario Land: Daisy debuted in this game.
Vs. Ice Climber: The Ice Climbers debuted in this game.- The Legend of Zelda: Ocarina of Time: Sheik, Young Link and Ganondorf debuted in this game.
- Dr. Mario: Dr. Mario debuted in this game.
- Pokémon Gold and Silver: Pichu debuted in this game.
Fire Emblem: Shadow Dragon and the Blade of Light: Marth debuted in this game.- Fire Emblem Awakening: Lucina, Robin and Chrom debuted in this game.
Super Smash Bros. Melee: Roy debuted in this game.
Ball: Mr. Game & Watch debuted in this game.- Kirby's Adventure: Meta Knight debuted in this game.
Kid Icarus: Pit and Palutena debuted in this game.- Kid Icarus: Uprising: Dark Pit debuted in this game.
- Metroid: Zero Mission: Zero Suit Samus debuted in this game.
- Super Mario Land 2: Six Golden Coins: Wario debuted in this game.
Metal Gear: Snake debuted in this game.- Donkey Kong Country: Diddy Kong and King K. Rool debuted in this game.
- Mother 3: Lucas debuted in this game.
Sonic the Hedgehog (1991): Sonic debuted in this game.
Pikmin: Olimar debuted in this game.- Pikmin 3: Alph debuted in this game.
- Pokémon Diamond and Pearl: Lucario debuted in this game.
Stack-Up: R.O.B. debuted in this game.- The Legend of Zelda: A Link to the Past & Four Swords: Toon Link debuted in this game.
- Star Fox 64: Wolf debuted in this game.
Doubutsu no Mori: Villager debuted in this game.
Mega Man: Mega Man debuted in this game.
Wii Fit: Wii Fit Trainer debuted in this game.- Super Mario Galaxy: Rosalina & Luma debuted in this game.
Punch-Out!!: Little Mac debuted in this game.- Pokémon X and Y: Greninja debuted in this game.
- Super Smash Bros. for Nintendo 3DS: The Mii Fighters debuted in this game.
PAC-MAN: PAC-MAN debuted in this game.
Xenoblade Chronicles: Shulk debuted in this game.- Super Mario Sunshine: Bowser Jr. debuted in this game.
- Super Mario Bros. 3: The Koopalings debuted in this game.
Duck Hunt: Duck Hunt Duo debuted in this game.
Street Fighter: Ryu and Ken debuted in this game.
Final Fantasy VII: Cloud and Sephiroth debuted in this game.- Fire Emblem Fates: Corrin debuted in this game.
Bayonetta: Bayonetta debuted in this game.
Splatoon: Inkling debuted in this game.
Castlevania: Simon debuted in this game.- Castlevania: Rondo of Blood: Richter debuted in this game.
- Animal Crossing: New Leaf: Isabelle debuted in this game.
- Pokémon Sun and Moon: Incineroar debuted in this game.
Persona 5: Joker debuted in this game.
Dragon Quest XI: Hero (Luminary) debuted in this game.- Dragon Quest III: Hero (Erdrick) debuted in this game.
- Dragon Quest IV: Hero (Solo) debuted in this game.
- Dragon Quest VIII: Hero (Eight) debuted in this game.
- Diddy Kong Racing: Banjo debuted in this game.
Banjo-Kazooie: Kazooie debuted in this game.
Fatal Fury: King of Fighters: Terry debuted in this game.- Fire Emblem Heroes: Byleth debuted in this game.
ARMS: Min Min debuted in this game.- Final Fantasy VII: Cloud and Sephiroth debuted in this game.
Minecraft: Java Edition: Steve debuted in this game.- Xenoblade Chronicles 2: Pyra and Mythra debuted in this game.
Tekken: Kazuya debuted in this game.
Kingdom Hearts: Sora debuted in this game.
Stages
- Super Smash Bros. Ultimate
- Super Mario 64: Peach's Castle, Princess Peach's Castle and Rainbow Cruise originate from this game.
Yoshi's Story: Super Happy Tree and Yoshi's Story originate from this game.- Donkey Kong 64: Jungle Japes is named after the first world in this game.
- The Legend of Zelda: Majora's Mask: Great Bay originates from this game.
- Zelda II: The Adventure of Link: Temple originates from this game.
- Pokémon Stadium: Pokémon Stadium is named after this game.
- Super Mario Bros. 2: Mushroom Kingdom II is based on this game.
- Luigi's Mansion: Luigi's Mansion originates from this game.
- Mario Kart DS: Figure-8 Circuit is named after a track from this game.
- The Legend of Zelda: Twilight Princess: Bridge of Eldin originates from this game.
- The Legend of Zelda: Wind Waker: Pirate Ship originates from this game.
- Super Mario World 2: Yoshi's Island: Yoshi's Island originates from this game.
- Kirby Super Star: Halberd and The Great Cave Offensive originate from this game.
- Pokémon Stadium 2: Pokémon Stadium 2 is named after this game.
- F-Zero GX: Port Town Aero Dive originates from this game.
WarioWare, Inc.: Mega Microgame$!: WarioWare, Inc. is based on this game.- WarioWare: Touched!: The "Blowin' Up" and "Lose Your Marble" microgames in WarioWare, Inc. originate from this game.
- Animal Crossing: Wild World: Smashville is based on this game.
Vs. Balloon Fight: The fish in Summit originates from this game.- Mario Bros.: Mario Bros. is based on this game.
Electroplankton: Hanenbow originates from this game.- Metal Gear Solid: Shadow Moses Island originates from this game.
- Electroplankton: Hanenbow originates from this game.
- Super Mario 3D Land: 3D Land is based on this game.
- New Super Mario Bros. 2: Golden Plains is based on this game.
- Super Mario 3D Land: 3D Land is based on this game.
- Paper Mario: Sticker Star: The first and third portions of Paper Mario originate on this game.
- Paper Mario: The Thousand-Year Door: The second portion of Paper Mario originates on this game.
- The Legend of Zelda: Spirit Tracks: Spirit Train originates from this game.
- Pokémon Black and White: Unova Pokémon League originates from this game.
- The Legend of Zelda: Spirit Tracks: Spirit Train originates from this game.
- EarthBound Beginnings: Magicant originates from this game.
Nintendogs: Living Room is based on this game.- Nintendogs + Cats: Living Room is modeled after the "Country Home" from this game.
Find Mii II: Find Mii is based on this game.
Tomodachi Life: Tomodachi Life is based on this game.- Find Mii II: Find Mii is based on this game.
PictoChat: PictoChat 2 is based on this game.- Mega Man 2: Wily Castle's design originated in this game.
- New Super Mario Bros. U: Mushroom Kingdom U is based on this game.
- Mario Kart 8: Mario Circuit originates from this game.
- The Legend of Zelda: Skyward Sword: Skyloft originates from this game.
- Lion: This game is featured as one of the areas in Flat Zone X.
- Chef: This game is featured as one of the areas in Flat Zone X.
- Oil Panic: This game is featured as one of the areas in Flat Zone X.
- Helmet: This game is featured as one of the areas in Flat Zone X
- Manhole: The character from this game appears in the Helmet area in Flat Zone X.
- Game & Wario: Gamer originates from this game.
- Animal Crossing: City Folk: Town and City is based on this game.
Vs. Wrecking Crew: Wrecking Crew is based on this game.
Pilotwings: The red plane in Pilotwings originates from this game.- Pilotwings Resort: The yellow plane in Pilotwings originates from this game.
Wii Sports Resort: Several aspects of the Wuhu Island originate from this game.- Sonic Lost World: Windy Hill Zone originates from this game.
- Pac-Land: PAC-LAND is based on this game.
- Super Mario Odyssey: New Donk City Hall originates from this game.
- The Legend of Zelda: Breath of the Wild: Great Plateau Tower originates from this game.
- Tekken 7: Mishima Dojo originates from this game.
Items
- Kirby Air Ride: The Dragoon debuted in this game.
- Super Mario Bros.: The Lost Levels: The Poison Mushroom debuted in this game.
- Super Mario Kart: The Lightning Bolt debuted in this game.
Panel de Pon: The Lip's Stick debuted in this game.- Super Scope 6: The Super Scope debuted in this game.
- Steel Diver: The Steel Diver debuted in this game.
- Clu Clu Land: The Unira debuted in this game.
- Soccer: The Soccer Ball debuted in this game.
- Super Mario Strikers: The Soccer Ball's ability to catch fire debuted in this game.
