Ghost may refer to:
- Blinky, Inky, Pinky, and Clyde, the four ghosts from the Pac-Man universe.
- Ghost, an enemy in Smash Run from the Find Mii universe.
- Boo, a ghost enemy from the Mario universe.
- Ghosts from Luigi's Mansion, enemies from the Mario universe.
- Ghosts from Luigi's Mansion: Dark Moon, appearing as a trophy in Super Smash Bros. for Nintendo 3DS.
- Ghost-type Pokémon from the Pokémon series, including Gastly, Chandelure, Giratina, and Honedge.
- Poltergust 5000, named Ghost Vacuum in Japan, which Luigi uses in his Final Smash in SSB4.
- The Support Ghost in Yoshi's Island.
- Ghost, a smasher from New Jersey.