Multi-Man Melee is a single player mode in Melee that pits the player's character against a team of Fighting Wire Frames in various situations. Different modes within Multi-Man Melee include:
- 10-Man Melee, in which the player must defeat 10 Wire Frames without falling.
- 100-Man Melee, in which the player must defeat 100 Wire Frames without falling.
- 3-Minute Melee, in which the player must defeat as many Wire Frames as possible without falling, during this period of time.
- 15-Minute Melee, in which the player must defeat as many Wire Frames as possible without falling, during this period of time.
- Endless Melee, in which the player must defeat as many Wire Frames as possible before falling.
- Cruel Melee, in which the player must defeat as many Wire Frames, with high handicaps and increased aggressiveness, as possible. This mode is famous for its involvement in the Sonic and Tails rumor spread by Electronic Gaming Monthly: that after defeating 20 Wire Frames in a single round, Sonic and Tails will challenge the player and become available characters. This rumor has proven false both in premise and in practice - not only would it be highly unlikely that SEGA (which, at Melee's release, was not yet a third party company) would sell its characters for use in a Nintendo game, but Cruel Melee strategies proved very quickly that Sonic and Tails did not appear after obtaining 20 kills. Also, the Mr. Resetti Trophy is unlocked in Cruel Melee by defeating 5 opponents.
There is also a 30-Man Melee in Adventure mode. The Event Match Legendary Pokémon is also sometimes called a Multi-Man Melee, due to the goal of defeating several Wire Frames.